Лимфома Ходжкина и «новый старый» бендамустин

КЛИНИКА, ДИАГНОСТИКА И ЛЕЧЕНИЕ ЛИМФОИДНЫХ ОПУХОЛЕЙ , , ,

С.С. Шкляев, В.В. Павлов

ФГБУ МРНЦ МЗ РФ, Обнинск, Российская Федерация

РЕФЕРАТ

Лимфома Ходжкина — злокачественная опухоль, которая с течением времени превратилась из фатальной неизлечимой болезни в успешно вылечиваемую в подавляющем большинстве случаев. Тем не менее прогноз у пациентов с рефрактерным и рецидивирующим течением заболевания нередко плохой и угрожающий жизни, в особенности в тех случаях, когда прогрессирование опухоли продолжается после высокодозной химиотерапии с трансплантацией аутологичных гемопоэтических стволовых клеток или, у некоторых пациентов, даже после аллогенной трансплантации костного мозга. Бендамустин — «новый старый» цитостатический препарат, который может эффективно применяться при лечении таких больных. Представляемый нами обзор литературы отводит важное место целому ряду новых возможных вариантов лечения лимфомы Ходжкина с применением бендамустина.

Ключевые слова: лимфома Ходжкина, рефрактерное и рецидивирующее течение, лечение, бендамустин.

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