позвоночник

Малоинвазивные хирургические технологии при поражениях позвоночника в онкогематологии

ХИРУРГИЧЕСКИЕ ТЕХНОЛОГИИ ПРИ ЛИМФОИДНЫХ ОПУХОЛЯХ , , , ,

А.К. Валиев, А.В. Соколовский, А.С. Неред, Э.Р. Мусаев

ФГБУ «РОНЦ им. Н.Н. Блохина» РАМН, Москва, Российская Федерация

РЕФЕРАТ

В последние десятилетия отметилась четкая тенденция к росту злокачественных новообразований с поражением костей скелета. Они составляют в среднем 1,5–2 % всех онкологических заболеваний. Наиболее распространены, по данным ряда авторов, множественная миелома (35–50 %), остеосаркома (20–30 %), хондросаркома (10–17 %), саркома Юинга (6–12 %), лимфомы (3–7 %). Соответственно и проблема лечения патологических переломов позвонков у больных с множественной миеломой и лимфомами становится более актуальной. Существующие современные малоинвазивные методы лечения патологических переломов позвонков (чрескожная вертебропластика и кифопластика) у больных множественной миеломой и лимфомами позволяют значительно улучшить качество жизни и в короткий срок начать специальное лечение.

Ключевые слова: позвоночник, вертебропластика, патологические переломы, множественная миелома, лимфомы.

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ЛИТЕРАТУРА

  1. Malawer M.M. Musculoskeletal Cancer Surgery. In: Treatment of Sarcomas and Allied Diseases. Ed. by M.M. Malawer, P.H. Sugarbaker. Washington: Kluwer Academic Publishers, 2001.
  2. Зацепин С.Т. Костная патология взрослых: Руководство для врачей. М.: Медицина, 2001. [Zatsepin S.T. Kostnaya patologiya vzroslykh: Rukovodstvo dlya vrachey (Bone disorders in adults: manual for medical practitioners). M.: Meditsyna, 2001.]
  3. Алиев М.Д. Злокачественные опухоли костей. M., 2008. [Aliyev M.D. Zlokachestvennyye opukholi kostey (Malignant bone tumors). M., 2008.]
  4. Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразо- ваний в России и странах СНГ в 2009 г. Вестн. онкол. 2011; 22(3 Прил. 1). [Davydov M.I., Aksel E.M. Statistika zlokachestvennykh novoobrazovaniy v Rossii i stranah SNG v 2009 g. (Statistics of malignancies in Russia and CIScountries in 2009). Vestn. onkol. 2011; 22(3 Suppl. 1).]
  5. Kyle R.A., Rajkumar S.V. Multiple myeloma. Blood 2008; 111: 2962–72.
  6. Rehak S., Maisnar V., Malek V. et al. Diagnosis and surgical therapy of plasma cell neoplasia of spine. Neoplasma 2009; 56: 84.
  7. Mendoza S., Urrutia J., Fuentus D. Surgical treatment of solitary plasmocytoma of the spine: case series. Iowa Orthopaed. J. 2004; 24: 86–94.
  8. McDonald R.J., Trout A.T., Gray L.A. et al. Vertebroplasty in Multiple Myeloma: Outcomes in a Large Patient Series. Am. J. Neuroradiol. 2008; 29: 642–8.
  9. Garland P., Gishen P., Rahemtulla A. Percutaneous vertebroplasty to treat painful myelomatous vertebral deposits — long term efficacy outcomes. Ann. Hematol. 2010 Jul 6.
  10. Dimopoulos M.A., Moulopolos L.A., Maniatis A., Alexenian R. Solitary plasmacytoma of bone and asymptomatic multiple myeloma. Blood 2000; 96: 2037–44.
  11. Hu K., Yahalom J. Radiotherapy in the management of plasma cell tumors. Oncology 2000; 14: 101–8.
  12. Maruyama D., Watanabe T., Beppu Y. et al. Primary Bone Lymphoma: A New and Detailed Characterization of 28 Patients in a Single-Institution Study. Hematol. Stem Cell Transplant. Div. 2006; 56–67.
  13. Cortet B., Cotton., Boutry N. et al. Percutaneous vertebroplasty in patients with osteolytic metastases or multiple myeloma [see comments]. Rev. Rheum. Engl. Ed. 1997; 64(3): 177–83.
  14. Durr H.R., Muller P.E., Hiller E. et al. Malignant lymphoma of bone. Arch. Orthopaed. Trauma Surg. 2002; 122: 10–6.
  15. Lecouvet F.E., Van den Berg B.C, Maldague B.E. et al. Vertebral compression fractures in multiple myeloma. Part I. Distribution and appearance at MR imaging. Radiology 1997; 204: 195–9.
  16. Durr H.R., Wegener B., Krodel A. et al. Multiple myeloma: surgery of the spine: retrospective analysis of 27 patients. Spine 2002; 27: 320–6.
  17. Kyle R.A., Gertz M.A., Witzing T.E. et al. Review of 1027 patients with newly diagnosed multiple myeloma. Mayo Clin. Proc. 2003; 78(1): 21–33.
  18. Chahal S., Lagera J.E., Ryder J., Kleinschmidt-DeMasters B.K. Hematological neoplasms with first presentation as spinal cord compression syndromes: a 10-year retrospective series and review of the literature. Clin. Neuropathol. 2003; 22(6): 282–90.
  19. Chiodo A. Spinal cord injury caused by epidural B-cell lymphoma: report of two cases. J. Spinal Cord Med. 2007; 30(1): 70–2.
  20. Rao G., Chul S.H., Chakrabarti I.I. et al. Multiple Myeloma of the cervical spine: treatment strategies for pain and spinal instability. J. Neurosurg. Spine. 2006; 5: 140-145.
  21. Kwon A.-H., Chang U.-K., Gwak H.-S. et al. The Role of Surgery in the Treatment of Spinal Myeloma. J. Korean Neurosurg. Soc. 2005; 37: 187–92.
  22. Masala S., Fiori R., Massari F. et al. Percutaneus kyphoplasty: indications and technique. Tumori 2004; 90: 22–6.
  23. Slatkin N. Cancer-Related Pain and its Pharmacologic Management in the Patients With Bone Metastasis. J. Support Oncol. 2006; 4(Suppl. 1): 015–21.
  24. Алиев М.Д., Долгушин Б.И., Валиев А.К. и др. Чрезкожная вертебро- пластика в онкологии. М.: Издательская группа РОНЦ, 2008: 43–54. [Aliyev M.D., Dolgushin B.I., Valiyev A.K. i dr. Chrezkozhnaya vertebroplastika v onkologii (Transcutaneous vertebroplasty in oncology). M.: Izdatelskaya gruppa RONTS, 2008: 43–54.]
  25. Deramond H., Dion J.E., Chiras J. Complications in vertebroplasty. In: Percutaneous Vertebroplasty. Ed. by J.M. Mathis, H. Deramond, S.M. Belkoff. New York: Springer-Verlag, 2002: 165–73.
  26. Kaemmerlen P., Thiesse P., Jonas P. et al. Percutaneous injection of orthopedic cement in metastatic vertebral lesions [letter]. N. Engl. J. Med. 1989; 321(2): 121.
  27. Komemushi A., Tanigawa N., Kariya S. et al. Percutaneous vertebroplasty for compression fracture: analysis of vertebral body volume by CT volumetry. Acta Radiol. 2005; 46: 276–9.
  28. Валиев А.К., Мусаев Э.Р., Тепляков В.В. и др. Чрезкожная вертебро- пластика в онкологии. М.: ИНФРА-М, 2010: 69. [Valiyev A.K., Musaev E.R., Teplyakov V.V. i dr. Chrezkozhnaya vertebroplastika v onkologii (Transcutaneous vertebroplasty in oncology). M.: INFRA-M, 2010: 69.]
  29. Каллистов В.Е. Метастатические опухоли позвоночника (клиника, диагностика, лечение): Дис. ¼ канд. мед. наук. М., 1999. [Kallistov V.E. Metastaticheskiye opukholi pozvonochnika (klinika, diagnostika, lecheniye): Avtoref. dis. … kand. med. nauk (Metastatic spinal tumors (presentation, diagnosis, management)). Author’s summary of dissertation for the degree of Candidate of medical sciences. M., 1999.]
  30. Wetzel F.T., Maurer P., Thompson K. et al. Minimally Invasive Spine Surgery: A Surgical Manual. Spine 2001; 25: 382–8.
  31. Boriani S., Gasparrini A., Paderni S., Bandiera S., Cappucio M. Terapia chirurgica delle lesioni vertebralinel mieloma. Haematologica 2004; 89: 21–3.
  32. Schiff D. Spinal cord compression. Neurol. Clin. 2003; 21: 67–86.
  33. Walker M.P., Yaszemski M.J., Kim C.W. et al. Metastatic disease of the spine: evaluation and treatment. Clin. Orthop. 2003; 415: S165–75.
  34. Sharma B.S., Gupta S.K., Khosla V.K. et al. Midline and far lateral approaches to foramen magnum lesions. Neurol. India 1999; 47: 268–71.
  35. Chiras J., Deramond H. Complications des vertebroplasties. In: Echecs et Complications de la Chirurgie du Rachis. Chirurgie de Reprise. Ed. by G. Sailant, C. Laville. Paris: Sauramps Medical, 1995: 149–53.
  36. Cyteval C., Sarrabere M.P., Roux J.O. et al. Acute osteoporotic vertebral collapse: open study on percutaneous injection of acrylic surgical cement in 20 patients. Am. J. Roentgenol. 1999; 173(6): 1685–90.
  37. Li K.C., Poon P.Y. Sensitivity and specificity of MRI in detecting malignant spinal cord compression and in distinguishing malignant from benign compression fractures of vertebrae. Magn. Reson. Imaging 1988; 6: 547–56.
  38. Anselmetti G.C., Corgnier A., Debernardi F. et al. Treatment of painful compression vertebral fractures with vertebroplasty: results and complications. Radiol. Med. (Torino) 2005; 110: 262–72.
  39. Grados F., Depriester C., Cayrolle G. et al. Long-term observations of vertebral osteoporotic fractures treated by percutaneous vertebroplasty. Rheumatology (Oxford) 2000, 39: 1410–4.
  40. Uppin A.A., Hirsch J.A., Centenera L.V. et al. Occurrence of new vertebral body fracture after percutaneous vertebroplasty in patients with osteoporosis. Radiology 2003; 226: 119–24.
  41. Harrop J.S., Prpa B., Reinhardt M.K. et al. Primary and Secondary Osteoporosis’ Incidence of Subsequent Vertebral Compression Fractures After Kyphoplasty. Spine 2004; 29: 2120–5.
  42. Синельников Р.Д. Атлас анатомии человека. Т. I. М.: Медицина, 1972. [Synelnikov R.D. Atlas anatomii cheloveka (Atlas of human anatomy). T. I. M.: Meditsyna, 1972.]
  43. O’Brien J.P., Sims J.T., Evans A.J. Vertebroplasty in patients with severe vertebral compression fractures: a technical report. Am. J. Neuroradiol. 2000; 21(8): 1555–8.
  44. Dahl O.E., Garvik L.J., Lyberg T. Toxic effects of methylmetacrylate monomer on leukocytes and endothelial cells in vitro [published erratum appeared in Acta Orthop Scand. 1995; 66(4): 387]. Acta Orthop. Scand. 1994; 65(2): 147–53.
  45. Belkoff S.M., Mathis J.M., Jasper L.E. et al. The biomechanics of vertebroplasty: the effect of cement volume on mechanical behavior. Spine 2001; 26(14): 1537–41.
  46. Barr J.D., Barr M.S., Lemley T.J. et al. Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine 2000; 25(8): 923–8.
  47. Heini P.F., Walchli B., Berlemann U. Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A prospective study for the treatment of osteoporotic compression fractures. Eur. Spine J. 2000; 9: 445–50.