Т-клеточные лимфомы

Т-клеточные лимфомы: возможности терапии при ограниченном выборе

МОЙ ВЫБОР , , , ,

В.А. Доронин

ФГБУ «РОНЦ им. Н.Н. Блохина» РАМН, Москва, Российская Федерация

РЕФЕРАТ

Периферические и кожные Т-клеточные лимфомы (ПТКЛ и КТКЛ) представляют собой особую группу неходжкинских лимфом (НХЛ) с широким спектром молекулярных и генетических особенностей, а также разнообразными симптомами и клиническими проявлениями. Разнородность и редкость этих заболеваний создают трудности при проведении клинических исследований, а прогресс в лечении идет гораздо медленнее, чем при более распространенных В-клеточных НХЛ. Вследствие этого для Т-клеточных лимфом до настоящего времени не существует стандартов терапии. Лечение часто проводится в рамках клинических исследований. В статье рассматриваются оптимальные возможности терапии ПТКЛ и КТКЛ, обсуждаются также новые варианты лечения.

Ключевые слова: Т-клеточные лимфомы, периферическая Т-клеточная лимфома неуточненная, ангиоиммунобластная Т-клеточная лимфома, анапластическая крупноклеточная лимфома, кожные Т-клеточные лимфомы.

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