Influence of chemotherapy on reproductive system: methods of protection and preservation of ovarian function

M.V. Volochayeva1, R.G. Shmakov1, and Ye.A. Demina2

1 V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, RF Ministry of Health, Moscow, Russian Federation

2 N.N. Blokhin Russian Cancer Research Centre, RAMS, Moscow, Russian Federation


ABSTRACT

The recent studies showed the great importance of discussing the issue of protection and preservation of the ovarian function in cancer patients. Nowadays, when new effective methods of treatment are available, many cancer patients wish to realize their reproductive function. In this review, we discuss the methods of ovarian protection such as pharmacological protection and IVF program including a cryopreservation and transplantation of ovarian tissue or cryopreservation of oocytes and embryos.

Keywords: fertility preservation, cancer, cryopreservation tissue, oocytes, embryos

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