K.A. Panyushin, Yu.M. Potapkina, Ye.V. Ignatyeva, T.A. Moskovskaya, T.V. Zhbrykunova, and O.A. Rukavitsyn
N.N. Burdenko Principal Military Clinical Hospital, RF Ministry of Defense, Moscow, Russian Federation
ABSTRACT
37 patients with hematological disorders underwent complex neurological evaluation including examination by a neurologist and electroneuromyography (ENMG). It is found that the considerable portion (51.3 %) of hematological patients shows signs of polyneuropathy as early as at the time of diagnosis. The data obtained indicate the possible need in specific neurological treatment just at the time of the initial tumor diagnosis prior to chemotherapy. The doses of chemotherapeutic agents should also be discussed in order to decrease their adverse effect on the peripheral nervous system. The results obtained suggest that detection of any hematological disorder necessitates examination by a neurologist, and neurological monitoring in a hematological in-patient clinic is an important part of management of patients with hematological malignancies.
Keywords: lymphoproliferative diseases, polyneuropathy, ENMG, polychemotherapy
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