Historical Background of the Role of Bone Marrow Core Biopsy in the Staging System for Classical Hodgkin Lymphoma and the Current View in the Era of PET-CT: A Literature Review

AA Danilenko, NA Falaleeva, SV Shakhtarina

AF Tsyb Medical Radiological Research Centre, branch of the NMRC of Radiology, 4 Koroleva ul., Obninsk, Kaluga Region, Russian Federation, 249036

For correspondence: Anatolii Aleksandrovich Danilenko, MD, PhD, 4 Koroleva ul., Obninsk, Kaluga Region, Russian Federation, 249036; Tel.: +7(909)250-18-10; e-mail: danilenkoanatol@mail.ru

For citation: Danilenko AA, Falaleeva NA, Shakhtarina SV. Historical Background of the Role of Bone Marrow Core Biopsy in the Staging System for Classical Hodgkin Lymphoma and the Current View in the Era of PET-CT: A Literature Review. Clinical oncohematology. 2023;16(4):351–60. (In Russ).

DOI: 10.21320/2500-2139-2023-16-4-351-360


ABSTRACT

The staging of Hodgkin lymphoma lays the groundwork for optimal treatment decision making. For a long time, bone marrow assessment has been an integral part of staging. The study of bone marrow involvement in tumor progression includes radiological method and morphological analysis of its core biopsy samples. During the last five decades of using bone marrow core biopsy, the attitude of oncologists and hematologists to this invasive and painful procedure remained ambivalent between denying and affirming the need to carry it out in all or most Hodgkin lymphoma cases. The present review provides the historical background of bone marrow core biopsy and considers its appropriateness for patients with classical Hodgkin lymphoma.

Keywords: Hodgkin lymphoma, bone marrow, core biopsy.

Received: March 26, 2023

Accepted: September 2, 2023

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