Case of Pneumocystis Pneumonia after High-Dose Chemotherapy with Autologous Hematopoietic Transplantation

INFECTIONS IN ONCOHEMATOLOGY , ,

V.O. Sarzhevskii1, V.Ya. Mel’nichenk1, D.S. Kolesnikova1, O.Yu. Bronov1, V.M. Sotnikov2, N.N. Smol’tsova2

1 N.I. Pirogov National Medical and Surgical Centre under the Ministry of Health of the Russian Federation, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203

2 Russian Scientific Center of Roentgenoradiology under the Ministry of Health of the Russian Federation, 86 Profsoyuznaya str., Moscow, Russian Federation, 117997

For correspondence: V.O. Sarzhevskii, PhD, Associate Professor, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203; Tel: +7(495)603-72-18; e-mail: vladsar@pochta.ru

For citation: Sarzhevskii V.O., Mel’nichenko V.Ya., Kolesnikova D.S., Bronov O.Yu., Sotnikov V.M., Smol’tsova N.N. Case of Pneumocystis Pneumonia after High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Transplantation. Klin. Onkogematol. 2014; 7(4): 583–586 (In Russ.).

ABSTRACT

Pneumocystis pneumonia is a rare complication of a high-dose chemotherapy and autologous bone marrow/peripheral hematopoietic stem cells transplantation in patients with hematological malignances. The absence of typical clinical symptoms and the probability of a lethal outcome require a special approach to this problem. A brief review of literature and presented clinical case give an idea of clinical manifestations, course, diagnostic approaches, prevention, and treatment of pneumocystis pneumonia in this category of patients.

Keywords: autologous bone marrow transplantation, high-dose chemotherapy, pneumocystis pneumonia

Accepted: September 19, 2014

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