SURGERY IN ONCOHEMATOLOGY

Recommendation for Sedation and General Anesthesia in Different Tests and Procedures in Pediatric Oncohematology

SURGERY IN ONCOHEMATOLOGY , ,

NV Matinyan, TT Valiev

NN Blokhin Russian Cancer Research Center, 24 Kashirskoye sh., Moscow, Russian Federation, 115478

For correspondence: Nune Vanunievna Matinyan, DSci, 24 Kashirskoye sh., Moscow, Russian Federation, 115478; Tel: +7(499)324-32-12; e-mail: n9031990633@yandex.ru

For citation: Matinyan NV, Valiev TT. Recommendation for Sedation and General Anesthesia in Different Tests and Procedures in Pediatric Oncohematology. Clinical oncohematology. 2017;10(1):108–12 (In Russ).

DOI: 10.21320/2500-2139-2017-10-1-108-112

ABSTRACT

Current anti-tumor chemotherapy programs for pediatric oncohematological disorders treatment imply diagnostic and therapeutic procedures under sedation. Based on the international and our own experience, this paper lists recommendations for the optimal anesthesia method for different manipulations in oncohematology.

Keywords: anesthesia, oncohematology, children.

Received: August 1, 2016

Accepted: December 12, 2016

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REFERENCES

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  4. Горобец Е.С. Анестезиологические проблемы трахеобронхиальной обструкции у больных с опухолями средостения: Автореф. дис. ¼ д-ра мед. наук. М., 1993. 44 с.
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Technical Problems of Splenectomy in Hematological Diseases

SURGERY IN ONCOHEMATOLOGY , , ,

SR Karagyulyan, KI Danishyan, SA Shutov, MA Silaev

Hematology Research Center under the Ministry of Health of the Russian Federation, 4а Novyi Zykovskii pr-d, Moscow, Russian Federation, 125167

For correspondence: Karen Ismailovich Danishyan, PhD, 4а Novyi Zykovskii pr-d, Moscow, Russian Federation, 125167; e-mail: ntanisian@gmail.ru

For citation: Karagyulyan SR, Danishyan KI, Shutov SA, Silaev MA. Technical Problems of Splenectomy in Hematological Diseases. Clinical oncohematology. 2017;10(1):101–7 (In Russ).

DOI: 10.21320/2500-2139-2017-10-1-101-107

ABSTRACT

The article focuses on the technical aspects of splenectomy (SE) in 1628 patients using two main techniques: laparoscopy (885 SEs) and laparotomy (743 SEs), with a description of various factors that influence the invasiveness and the success of the surgery. The fact is that in addition to the shape and size of an enlarged spleen, the technical complexity of the SE, especially in laparoscopic access depends on the following factors: perisplenitis, close presentation and fusion of the tail of the pancreas to the spleen, tumor infiltration of splenic vascular pedicle, branchy type of its structure, visceral obesity, compression of the splenic pedicle with enlarged and united lymph nodes. In most cases (60 %), there is a combination of several risk factors, thus making the surgery even more difficult. The indications for splenectomy, as well as its influence on the course of the main hematological disease are not considered in this paper.

Keywords: hematological disorders, splenectomy, laparoscopy, laparotomy.

Received: August 11, 2016

Accepted: November 14, 2016

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REFERENCES

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  7. Климанский В.А., Бекназаров Я.Б. Опасности и осложнения спленэктомии у больных с заболеваниями системы крови. Хирургия. 1986;1:88–92.
    [Klimanskii VA, Beknazarov YaB. Hazards and complications of splenectomy in patients with hematological diseases. Khirurgiya. 1986;1:88–92. (In Russ)]
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Extensive Combined Surgeries in Patients with Blood Diseases and Gastric Cancer

SURGERY IN ONCOHEMATOLOGY , , , ,

S.R. Karagyulyan, K.I. Danishyan, A.V. Grzhimolovskii, V.S. Shavlokhov, S.A. Shutov, M.A. Silaev, L.G. Kovaleva, O.M. Sorkina, A.Yu. Bulanov

Hematology Research Center of RF MH, Moscow, Russian Federation

For citation: Karagyulyan S.R., Danishyan K.I., Grzhimolovskii A.V., Shavlokhov V.S., Shutov S.A., Silaev M.A., Kovalyova L.G., Sorkina O.M., Bulanov A.Yu. Extensive Combined Surgeries in Patients with Blood Diseases and Gastric Cancer. Klin. onkogematol. 2014; 7(3): 335–42 (In Russ.).

ABSTRACT

The second tumor in patients with myelo- or lymphproliferative diseases is not rare. However, the state of patients’ hemostasis and severely enlarged spleen can become a contraindication for a surgical intervention in a general surgery unit. Four cases of a successful gastrectomy with expanded lymphodissection are presented in a 53 year old woman with subleukemic myelosis (primary myelofibrosis according to WHO classification) and giant splenomegaly (38 ´ 21 ´ 13 cm, spleen weight: 4500 g) and in a 68 year old man with diffuse large В-cell lymphoma and massive splenomegaly (22 ´ 12 ´ 8 cm, spleen weight: 2850 g). Intraoperative compensated blood loss in both cases was 3800 ml and 3740 ml, respectively. Two patients had mild hemophilia A. Specially designed transfusional and anaesthetic strategy was required in all cases because of hemostatic disorders.

Keywords: stomach cancer, surgical treatment, hemophilia, myelofibrosis, lymphoma.

Address correspondence to: max-blood@mail.ru

Accepted: May 28, 2014

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